Respect Not Just Your Elders But Also Your Liver!

Black And Decker Brew N Go

In my explore for this report my appreciation and respect for the liver has grown exponentially. Your liver is an astounding organ and one of the most leading organs in your body. settled in the upper right quadrant of the abdomen, the liver is the largest and most complicated organ of the body, and is responsible for:

o Cleansing and filtering the blood stream.

o The production of bile which is stored in the gallbladder. When released, bile aids in the digestion of fats while helping to rid the body of harmful substances.

o Producing other leading chemical compounds such as albumin, blood clotting factors, cholesterol, and Vitamin E.

o Converting amino acids and lipids into the straightforward sugar glucose. This requires a complicated process catalyzed by a series of enzymes.

o Storing glucose in the form of glycogen. This process plays a needful role in maintaining general blood sugar levels.

o Proper metabolism of protein and fats.

o Metabolizing many medications, alcohol, and other ingested chemicals such as caffeine.

o The storage of vitamins A, B12, D, several of the other B vitamins, and minerals like iron and copper.

o Detoxifying the body from numerous substances like ammonia and metabolic wastes.

All in all over 500 chemical and metabolic functions take place in the liver. It filters about 2 quarts of blood per little manufacture it the "garbage disposal" of the body. And, if you retell these bullet points closely, you can see how the liver is complicated in diet, metabolism, blood sugar control, digestion, detoxification and elimination. It is critically leading to understand both how the liver works and what you can do to keep the liver properly. Your full, health and wellness, as well as how you age and fight disease, will be impacted by the health of your liver.

In Our Overly Medicated and Chemical World!

We live in an environment that has seen an increased use of chemicals and medication to process foods and treat symptoms. It is estimated that 80 percent of U.S. Livestock and poultry receive some animal drugs/hormones/antibiotics during their lifetime. Pesticides, herbicides, and other chemical storage methods are commonly used in food production. Add environmental toxins, chemical additives, genetic engineering, processing and refining practices, coupled with substance abuse and you can see why today's liver has been stressed like never before. Add to this the fact that the majority of the American diet, in both food and drink, creates an acidic environment that also stresses the liver, as well as other corporal systems, and you will begin to understand why we are looking so many citizen living lives compromised by degenerative diseases.

Detoxification and Cancer!

I've written a series of articles about the Acid - Alkaline deliberate upon as it regards cancer and degenerative diseases. The same can also apply to the liver. There are many in the scientific community who believe that up to 90% of all cancers are related to the effects of environmental carcinogens, such are found in cigarette smoke, food, water, and air. join this with deficiencies of the nutrients the body needs for allowable functioning of the detoxification and immune systems and you have a formula for increased susceptibility to cancer. allowable functioning of your liver's detoxification principles is critically leading for your body's potential to forestall cancer. The beauty of insight what you need to do to properly keep the liver will also have a positive ensue on your immune principles and helping your body stay slightly alkaline which is what it desires.

Your Liver is Your Detoxification Center.

The rest of this report will look at the methods your liver uses to detoxify your body and what you need to do to keep it working properly. First up is:

The Liver Filter - Your blood flows through the liver in such a way that it is filtered of toxic matter such as dead cells, chemicals, drugs, and particulate debris in the blood stream. This liver filter is called the sinusoidal system. It has specialized cells known as Kupffer cells that ingest and breakdown toxic matter. Your liver filter also removes a wide range of microorganisms such as bacteria, fungi, viruses, and parasites that might be in your blood stream. When working properly, the liver usually clears 99% of the bacteria and other toxins during this filtering process, and like any filter, it needs to be cleansed. Unlike the oil filter in your car which you can remove and replace fairly easily, the liver is a bit different. Although it can re-grow itself and can be transplanted, you in effect want to take steps daily to help verbalize its potential to filter, cleanse and detoxify you. We talk about this in my report "14 Steps to Cleansing and Supporting Your Liver!"

Every drug, artificial chemical, pesticide and hormone is metabolized by enzymatic pathways inside the liver cells. Now, I want you to stop and think this one through right now. It will be difficult for you to know what pesticides and hormones you might be curious in your food furnish but you can in effect tell what drugs and artificial chemicals you are taking in. Any drug you take has to be dealt with by the liver. Now, that doesn't mean going off your medication. But it does mean that for each medication you take you need to growth your keep to the liver. In addition, start reading the labels on your food packaging. If you eat fast food ask for the nutritional data for the products you are consuming. When you weigh out all you consume the greatest percentage of toxins you ingest is going to come through your food in the form of artificial chemicals, additives and ingredients.

Think of Yourself as One Giant Self-Storage Facility!

Many of the toxic chemicals that enter your body are fat-soluble. That presents a question since they will only dissolve in fatty or oily solutions and not water. These fat soluble chemicals are difficult for the body to excrete and if not handled by the liver they will be stored in the fat tissues and cell membranes, which are made of fatty substances. These toxins can be stored for years in the fat tissues. It is not uncommon that when citizen fast, begin to exercise, or go on a diet to sell out their percentage of body fat, they touch headaches, poor memory, stomach pain, nausea, fatigue, dizziness and palpitations. Sometimes they will have vivid memories of events in the past that are tied to a medication they used for some curative reason. This is usually caused by the stored toxins being released back into your principles and your liver is now forced to deal with them. Anytime you settle to sell out your percentage of body fat, you need to give extra keep to your liver.

The liver has two original mechanisms for converting fat-soluble chemicals into water soluble chemicals. This allows your body to in effect excrete them through its two main pathways: bile and urine. Now, here are some in effect big scientific names for these two original mechanisms the liver uses to detoxify you:

Phase One - Detoxification Pathway

Phase Two - Detoxification Pathway

No joke. These are two of the easier scientific names to remember. But it is just a set-up. When you look at the mechanisms in each of these phases those scientists throw in those hundred dollar words to try and mess with our brains. My goal is to try to explicate this in simpler terms. That way you can see what you will need to do nutritionally to keep these two phases.

Phase One - Detoxification Pathway.

There is a large group of enzymes that are collectively called Cytochrome P-450. These enzymes are settled in the membrane principles of the liver cells. In fact, these cells comprise the genetic coding to form many variations or isoenzymes of Cytochrome P-450 so that the liver can treat exact chemicals more effectively. To help the women understand this it would be like selecting the right style shoe for the right occasion. For the men it would be like selecting the right drill bit for your high speed Black 'n Decker.

Simply put, the phase one pathway converts a toxic chemical into a less harmful chemical through varied chemical reactions. That's the good news. The bad news is that these chemical reactions produce high levels of free radicals. I've written an report on free radical damage. face of genetics, free radical damage is considered by many to be the particular greatest factor in aging and degenerative diseases because it causes cell tissue damage. To counter this damage, your body needs antioxidants to discharge their destructive vigor and return the free radical molecule into a garage molecule. Antioxidants like vitamin C and E and natural carotenoids protect the liver cells from this free radical damage. But, far and away the most leading antioxidant for neutralizing the free radicals produced in Phase One is glutathione. We'll have more to say about glutathione in Phase Two.

Some of the Phase One enzymes directly neutralize some of the chemicals, but most of the chemicals are converted to intermediate forms that are much more chemically active. In increasing to the potential for free radical damage you also have a more toxic environment. If your Phase Two detoxification systems are not working properly, these intermediate forms can cause liver damage as well as set in motion carcinogenic processes. So, the equilibrium in the middle of the creation of Phase One intermediate forms and the potential of the Phase Two detoxification pathways to finish the process is also a needful issue. I hope you're beginning to see how needful your liver function is to your full, health.

I have one additional note on the P-450 enzyme principles that I would like to bring to your attention. Pesticides can disrupt the P-450 enzymatic principles by causing it to become over active. This might sound like a good thing, but for the liver it is not because high levels of damaging free radicals are produced. Without extra security from high concentrations of antioxidants the liver will be damaged from this increased free radical production. This is one of the reasons why pesticide usage on our food furnish has become such a health as well as an environmental issue.

Phase Two - Detoxification Pathway.

This is where the scientists team up with the English teachers to make our insight of this pathway more difficult. This pathway is commonly called the conjugation pathway. It is in this pathway that the liver cells add someone else substance to the chemical or drug toxin to render it less harmful and water-soluble. By manufacture the fat-soluble toxins water-soluble your body can now eliminate it through watery fluids such as bile or urine. There are six Phase Two detoxification pathways:

o Glutathione Conjugation

o Amino Acid Conjugation

o Methylation

o Sulfation

o Acetylation

o Glucuronidation

Don't you just love when scientists and English teachers get together to make our lives easier to understand. Well, hang with me and I will try to speak in terms that make sense.

For the enzyme systems in Phase Two to work properly, positive nutrients are needed to set in motion the enzyme systems as well as furnish the small molecules added to the toxins to neutralize them. This requires metabolic vigor which requires metabolic enzymes to help generate this energy. I wrote an report about the point of digestive enzymes to your full, health. I bring it up in this report because if your diet is lacking in digestive enzymes, then you force the pancreas to change metabolic enzymes into digestive enzymes which can impact Phase Two detoxification. Also, citizen with persisting fatigue syndrome, a magnesium scantness or lack of corporal performance can also touch a slow down in Phase Two detoxification.

The Cliff Notes Version of Glutathione Conjugation!

Glutathione is a tripeptide composed of three amino acids - cysteine, glutamic acid, and glycine. simply stated, glutathione conjugation produces water-soluble substances that are excreted in the urine via the kidneys. The elimination of heavy metals like mercury and lead are dependent upon enough levels of glutathione. If you remember from Phase One, glutathione is also an leading antioxidant.

Since glutathione conjugation is a original pathway in Phase Two detoxification and glutathione is the most leading antioxidant in Phase One detoxification, your body needs enough supplies of glutathione. If depleted in Phase One, then Phase Two detoxification will be compromised. This blend of free radical security and detoxification makes glutathione one of the most leading anti-carcinogens and antioxidants known. Thankfully, glutathione is ready through diet and synthesis. However, our glutathione levels decrease with age so supplementation in our diet with fresh fruits and vegetables, cooked fish and meats is important.

Warning to Smokers!

Smoking increases the rate of utilization of glutathione because the chemical nicotine must be neutralized in the liver. Additionally, the other chemical toxins in the cigarette generate high levels of free radicals to use up glutathione. Smokers not only do damage to their lungs and heart but also generate the potential for liver dysfunction.

The Cliff Notes Version of the Rest of the Conjugation Pathways!

There is more that could be said about each of the following five conjugation pathways but I'm going to be brief about each one of them.

o Amino Acids. Glycine, taurine, glutamine, arginine, and ornithine are amino acids used to join with and neutralize toxins.

o Methylation. This involves attaching methyl groups to toxins. S-adenosylmethionine or Sam is the most coarse methyl group and is synthesized from the amino acid methionine as well as the nutrients choline, vitamin B12 and folic acid.

o Sulfation. This involves attaching sulfur-containing compounds to toxins. The process is leading for detoxifying several drugs, food additives, and toxins from the intestinal bacteria. It is the main pathway that the body uses to eliminate steroid and thyroid hormones.

o Acetylation. This is the original pathway that the body uses to eliminate sulfa drugs. This pathway is especially sensitive to genetic distinction which may factor into why many citizen are allergic to sulfa drugs.

o Glucuronidation. This pathway combines glucuronic acid with toxins. Many of the commonly prescribed drugs along with aspirin, menthol, food additives such as benzoates, and some hormones, are eliminated thru this pathway.

To summarize the detoxification process into a straightforward flow sheet would look something like this:

Toxins enter your principles > Liver filters out toxins > Step One Detoxification Pathways > Step Two Detoxification Pathways > Toxins converted to water soluble waste products > Waste products eliminated from your body via > Gall Bladder as Bile released into your intestines to be eliminated through bowel movements or > Kidneys eliminated through your urine.

Not only is it leading that your liver work properly but the health of your gall bladder, intestines, and kidneys are also highly leading in this detoxification process.

This is a lot of data and it is given to you to help you understand the process of detoxification so that you have a greater respect for your liver. underground within this data are keys to helping you enhance the health of your liver. Some are quite positive and some need additional exposure to see the relationship. The companion report "14 Steps to Cleansing and Supporting Your Liver!" will put this data into a working plan that you can use to help enhance your liver's function and health.